Mosquito immunity
Autor(es): Hillyer, Julian F.
Resumo: Throughout their lifetime, mosquitoes are exposed to pathogens during feeding, through breaks in their cuticle and following pathogen-driven cuticular degradation. To resist infection, mosquitoes mount innate cellular and humoral immune responses that are elicited within minutes of exposure and can lead to pathogen death via three broadly defined mechanisms: lysis, melanization and hemocyte-mediated phagocytosis. This chapter reviews our current understanding of the mosquito immune system, with an emphasis on the physical barriers that prevent pathogens from entering the body, the organs and tissues that regulate immune responses and the mechanistic and molecular bases of immunity.
Palavras-Chave: Vector Anopheles-Gambiae; Nitric-Oxide Synthase; Malaria Parasite Infection; Adult Female Mosquito; Dopachrome Conversion Enzyme; Fibrinogen-Related Proteins; Complement-Like Protein; Gram-Negative-Bacteria; Yellow-Fever Mosquito; Aedes-Aegypti
Imprenta: Invertebrate Immunity, v. 708, p. 218-238, 2010
Descritores: Aedes aegypti - Immune response ; Aedes aegypti - Molecular structure
Data de publicação: 2010
