Malathion vs. Aedes aegypti (Linnaeus, Diptera: Culicidae) from different regions of Venezuela

Capa:Malathion vs. Aedes aegypti (Linnaeus, Diptera: Culicidae) from different regions of Venezuela

Autor(es): Molina de Fernandez, Darjaniva; Bastidas B, Danny M.; Figueroa Acosta, Luisa Elena


Resumo: In Venezuela, malathion has been widely used continuously in control programs for Aedes aegypti. Therefore, a study in mosquitoes from urban Areas with high dengue casuistry in the states of Amazonas, Aragua, Bolivar, Lara, Merida and Zulia was conducted to determine the status of this vector susceptibility to malathion, compared with the reference susceptible strain, Rockefeller. Bioassays were done on bottles treated with the insecticide malathion, 100ug/mL evaluating the diagnostic doses in 30 minutes and biochemical assays in microplates were performed to determine metabolic mechanisms associated with status against insecticide. The bioassay results showed that there is malathion susceptibility, which was confirmed by biochemical tests. However, significant differences were found among all strains assessed values of P<0.005 for esterases alpha (alpha), beta esterases (beta) and standard acetylcholinesterase (AChe) and inhibited acetylcholinesterase (Achei). The mean comparison test of Bonferroni showed similarity between the strains Rock, Amazon and Lara for esterases alpha and beta. Similarity was found between the strains Rock, Bolivar and Zulia for the Ache and Achei tests. This study concludes that malathion showed its potential use in controlling the dengue vector in the locations evaluated.


Palavras-Chave: Aedes Aegypti; Esterases; Malathion; Susceptibility


Imprenta: Boletin de Malariologia y Salud Ambiental, v. 53, n. 1, p. 46-55, 2013


Descritores: Aedes aegypti - Dengue


Data de publicação: 2013