Larvicidal activity of lignans identified in Phryma leptostachya var. asiatica roots against three mosquito species
Autor(es): Park, IK; Shin, SC; Kim, CS; Lee, HJ; Choi, WS; Ahn, YJ
Resumo: The insecticidal activity of phytochemicals isolated from the roots of Phryma leptostachya var. asiatica against third instar larvae of Culex pipiens pallens, Aedes aegypti, and Ocheratatos togoi was examined. The two constituents of P. leptostachya var. asiatica roots were identified as the leptostachyol acetate (1) and 8 -acetoxy-2,2',6-trimethoxy-3,4,4',5'-dimethylenedioxyphenyl-7,7'-dioxabicyclo-[3.3.0]octane (11) by spectroscopic analysis. Compound I was lethal to C. pipiens pallens, A. aegypti, and O. togoi at 10 ppm. Compound 11 showed weak or no insecticidal activity against three mosquito species at 10 ppm. The LC50 values of I against C. pipiens pallens, A. aegypti, and O. togoi were 0.41, 2.1, and 2.3 ppm, respectively. Naturally occurring P. leptostachya var. asiatica root-derived compounds merit further study as potential mosquito larval control agents or lead compounds.
Palavras-Chave: Natural Insecticides; Mosquito Larvicides; Mosquito; Phryma Leptostachya Var. Asiatica; Lignans
Imprenta: Journal of Agricultural and Food Chemistry, v. 53, n. 4, p. 969-972, 2005
Identificador do objeto digital: 10.1021/jf048208h
Descritores: Aedes aegypti - Biochemistry ; Aedes aegypti - Larvicide ; Aedes aegypti - Public health
Data de publicação: 2005
