Isolation and identification of a peptide and its cDNA from the mosquito Aedes aegypti related to Manduca sexta allatotropin
Autor(es): Veenstra, JA; Costes, L
Resumo: Immunocytochemistry revealed that an allatotropin-immunoreactive peptide is produced by several neuroendocrince cells in the abdominal ganglia of the mosquito Aedes aegypti. The immunoreactive peptide was isolated and its structure determined to be Ala-Pro-Phe-Arg-Asn-Ser-Glu-Met-Met-Thr-Ala-Arg-Gly-Phe-amide. A cDNA clone encoding this novel neuropeptide was shown to encode a single copy of this peptide. The cDNA is unusual in that the first seven ATGs are not used for translation initiation. (C) 1999 Elsevier Science Inc. All rights reserved.
Palavras-Chave: Neuropeptide; Juvenile Hormone; Oviduct; Insect
Imprenta: Peptides, v. 20, n. 10, p. 1145-1151, 1999
Identificador do objeto digital: 10.1016/S0196-9781(99)00117-5
Descritores: Aedes aegypti - Immunology
Data de publicação: 1999