Twelve-hour duration testing of cream formulations of three repellents against Amblyomma americanum
Autor(es): Carroll, J. F.; Benante, J. P.; Klun, J. A.; White, C. E.; Debboun, M.; Pound, J. M.; Dheranetra, W.
Resumo: The repellent efficacies of the U.S. military repellent 33% N,N-diethyl-3-methylbenzamide (deet), 10% and 20% (1S, 2'S) 2-methylpiperidinyl-3-cyclohexene-1-carboxamide (SS220) and 10% and 20% 1-methyl-propyl-2-(hydroxyethyl)-1-piperidinecarboxylate (Bayrepel) cream formulations on human volunteers against the lone star tick Amblyomma americanum (L.) were evaluated in a simulated forest floor environment over a 12-h testing period. At 2-h intervals, volunteers, with repellent applied in a 5-cm-wide band around each ankle, stood for 5 min in plastic tubs containing leaf litter and 100 host-seeking A. americanum nymphs. Ticks were allowed to remain on a volunteer's feet and ankles for an additional 5 min after the volunteer exited the tub. All repellent formulations provided high levels of protection for the entire 12 h. No ticks crossed 5-cm-wide bands of 20% SS220 and Bayrepel during any challenge, and thus 100% protection was afforded throughout the test. These formulations showed a long-lasting efficacy hitherto unknown in tick repellents intended for use on human skin.
Palavras-Chave: Personal protection; Field evaluation; Aedes aegypti; Ixodidae; Deet; Permethrin; Efficacy
Imprenta: Medical and Veterinary Entomology, v. 22, n. 2, p. 144-151, 2008
Identificador do objeto digital: 10.1111/j.1365-2915.2008.00721.x
Descritores: Aedes aegypti - Repellent
Data de publicação: 2008
