Plasmodium gallinaceum: A novel morphology of malaria ookinetes in the midgut of the mosquito vector

Autor(es): Vernick, KD; Fujioka, H; Aikawa, M


Resumo: Malaria ookinetes invade midgut epithelial cells of the mosquito vector from the bloodmeal in the lumen of the mosquito midgut, but the cellular interactions of ookinetes with the mosquito vector remain poorly described. We describe here a novel morphology of Plasmodium gallinaceum ookinetes in which the central portion of the ookinete is an elongated narrow tube or stalk joining the anterior and posterior portions of the parasite. We propose that the previously undescribed stalk-form ookinete may be an adaptation to facilitate parasite locomotion through the cytoplasm of mosquito midgut epithelial cells.


Palavras-Chave: Malaria; Ookinete; Mosquito; Aedes; Insect vectors; Anopheles


Imprenta: Experimental Parasitology, v. 91, n. 4, p. 362-366, 1999


Identificador do objeto digital: 10.1006/expr.1998.4388


Descritores: Aedes aegypti - Cell


Data de publicação: 1999