Cytochrome P450-encoding genes from the Heliconius genome as candidates for cyanogenesis
Autor(es)Chauhan, R.; Jones, R.; Wilkinson, P.; Pauchet, Y.; Ffrench-Constant, R. H.
ResumoCytochrome P450s are important both in the metabolism of xenobiotics and the production of compounds such as cyanogenic glucosides, which insects use in their defence. In the present study, we use transcriptomic and genomic information to isolate and name P450-encoding genes from the butterfly Heliconius melpomene. We classify each of the putative genes into its appropriate superfamily and compare the distribution of P450s across sequenced insects. We also identify homologues of two P450s known to be involved in cyanogenesis in the six-spot Burnet moth, Zygaena filipendulae. Classification of HeliconiusP450s should be an important step in the dissection of their role in the exploitation of their host plant, the passion vine Passiflora.
Palavras-ChaveCytochrome P450; Heliconius; Passiflora; Cyanogenesis; Transcriptomics
ImprentaInsect Molecular Biology, v. 22, n. 5, p. 532-540, 2013
Identificador do Objeto Digital10.1111/imb.12042
DescritoresAedes aegypti - Genome
Data de Publicação:2013