Copaifera multijuga ethanolic extracts, oil-resin, and its derivatives display larvicidal activity against Anopheles darlingi and Aedes aegypti (Diptera: Culicidae)
Autor(es): Tavares Trindade, Frances Tatiane; Stabeli, Rodrigo Guerino; Pereira, Antonio Almeida; Facundo, Valdir Alves; de Almeida e Silva, Alexandre
Resumo: Copaifera spp. is a common tree species found in the tropical region of Latin America, popularly known as copaiba or pau-d'alho. Oil-resin from different Copaifera species and its components present several biological activities such as antimicrobial, anti-inflammatory, antioxidant and insecticidal, including larvicidal activity against mosquitoes. Thus, bark and leaf ethanolic extracts, oil-resin, essential oil and alepterolic acid from Copaifera multijuga Hayne, Fabaceae, were tested as larvicides against the main malaria vector in the north of Brazil, Anopheles darlingi and also Aedes aegypti, the dengue vector. A. darlingi larval mortality was significantly higher than A. aegypti for most tested compounds. Bark and leaf extracts resulted in lower Lethal Concentrations (LC50) values for A. darlingi, 3 and 13 ppm, respectively, while the essential oil provided the lowest LC50 value for A. aegypti, 18 ppm. Despite of that, the lowest LC values were from the alepterolic acid for both species, i.e. 0.9 and 0.7 ppm for A. darlingi and A. aegypti, respectively.
Palavras-Chave: Copaifera multijuga; Anopheles darlingi; Aedes aegypti; Vector control
Imprenta: Revista Brasileira de Farmacognosia, v. 23, n. 3, p. 464-470, 2013
Identificador do objeto digital: 10.1590/S0102-695X2013005000038
Descritores: Aedes aegypti - Larvicide ; Aedes aegypti - Public health
Data de publicação: 2013
