Clinical and Epidemiological Characterization of the First Recognized Outbreak of Dengue Virus-Type 2 in Mozambique, 2014
Autor(es): Massangaie, Marilia; Pinto, Gabriela; Padama, Fernando; Chambe, Geraldo; da Silva, Mariana; Mate, Inocencio; Chirindza, Celia; Ali, Sadia; Agostinho, Saozinha; Chilaule, Daniel; Weyer, Jacqueline; le Roux, Chantel; Abilio, Ana Paula; Baltazar, Cynthia; Doyle, Timothy J.; Cliff, Julie; Paweska, Janusz; Gudo, Eduardo Samo
Resumo: Since the first reported epidemic of dengue in Pemba, the capital of Cabo Delgado province, in 1984-1985, no further cases have been reported in Mozambique. In March 2014, the Provincial Health Directorate of Cabo Delgado reported a suspected dengue outbreak in Pemba, associated with a recent increase in the frequency of patients with nonmalarial febrile illness. An investigation conducted between March and June detected a total of 193 clinically suspected dengue patients in Pemba and Nampula, the capital of neighboring Nampula Province. Dengue virus-type 2 (DENV-2) was detected by reverse transcriptase polymerase chain reaction in sera from three patients, and 97 others were classified as probable cases based on the presence of DENV nonstructural protein 1 antigen or anti-DENY immunoglobulin M antibody. Entomological investigations demonstrated the presence of Aedes aegypti mosquitos in both Pemba and Nampula cities.
Palavras-Chave: Fever; Transmission; Chikungunya; Tanzania; Malaria; Africa
Imprenta: American Journal of Tropical Medicine and Hygiene, v. 94, n. 2, p. 413-416, 2016
Identificador do Objeto Digital: 10.4269/ajtmh.15-0543
Descritores: Aedes aegypti - Chikungunya Fever ; Aedes aegypti - Epidemiology ; Aedes aegypti - Public health
Data de Publicação: 2016