Composition and immunotoxicity activity of essential oils from leaves of Zingiber officinale Roscoe against Aedes aegypti L
Autor(es): Moon, H. I.; Cho, S. B.; Kim, S. K.
Resumo: The leaves of Zingiber officinale Roscoe were extracted and the major essential oil composition and immunotoxicity effects were studied. The analyses were conducted by gas chromatography and mass spectroscopy (GC-MS) revealed that the essential oils of Z. officinale leaves. The Z. officinale essential oil yield was 0.26%, and GC/MS analysis revealed that its major constituents were Camphene (5.26%), Phellandrene (6.58%), Zingiberene (36.48%), Geranial (4.32%), beta -gurjunene (2.74%), and Citronellol beta -sesguiphellandrene (12.31%). The essential oil had a significant toxic effect against early fourth-stage larvae of Aedes aegypti L with an LC sub(50) value of 46.38 ppm and an LC sub(90) value of 84.32 ppm. Also, Camphene ( greater than or equal to 95.0%), Phellandrene ( greater than or equal to 95.0%), Zingiberene ( greater than or equal to 95.0%), Geranial ( greater than or equal to 95.0%), beta -gurjunene ( greater than or equal to 97.0%), and Citronellol ( greater than or equal to 95.0%) were tested against the F21 laboratory strain of A. aegypti. Zingiberene ( greater than or equal to 95.0%) and Citronellol ( greater than or equal to 95.0%) have medium activity with an LC sub(50) value of 99.55 ppm and 141.45 ppm. This indicates that other major compounds may play a more important role in the toxicity of essential oil.
Palavras-Chave: Chromatographic techniques; Oil and gas industry; Toxicity; Strains; Major constituents; Toxicity tests; Aquatic insects; Mortality causes; Immunotoxicity; Chemical composition; Citronellol; Gas chromatography; Camphene; Larvae; Leaves; Essential oils; Immune response; Aedes aegypti; Zingiber officinale
Imprenta: Immunopharmacology and Immunotoxicology, v. 33, n. 1, p. 201-204, 2011.
Descritores: Aedes aegypti - Immune response ; Aedes aegypti - Immunology
Data de publicação: 2011
