Chikungunya virus transmission potential by local Aedes Mosquitoes in the Americas and Europe
Autor(es): Vega-Rua, Anubis ; Lourenco-de-Oliveira, Ricardo; Mousson, Laurence; Vazeille, Marie; Fuchs, Sappho; Yebakima, Andre; Gustave, Joel; Girod, Romain; Dusfour, Isabelle; Leparc-Goffart, Isabelle; Vanlandingham, Dana L; Huang, Yan-Jang S; Lounibos, LPhilip; Mohamed Ali, Souand; Nougairede, Antoine; de Lamballerie, Xavier; Failloux, Anna-Bella
Resumo: More than one million chikungunya cases have been reported in the Americas since October 2013, when the Asian genotype of chikungunya virus (CHIKV) was imported by a traveller returning from Asia. CHIKV is mainly transmitted in urban areas by the domestic mosquitoes Aedes aegypti and Aedes albopictus. In this study, we evaluate the potential for the CHIKV circulating in the Caribbean to initiate outbreaks in Aedes-infested regions of continental America and Europe by assessing the ability of local mosquitoes to experimentally transmit the virus. Mosquitoes were exposed to a blood-meal containing the virus which must overcome several barriers to infect various tissues in the vector before being secreted in the mosquito saliva when biting a host. We found that Ae. aegypti and Ae. albopictus transmitted similarly the virus. When exposing Ae. albopictus from Europe at a temperature of 20 degree C after infection, we detect a significant drop of CHIKV transmission potential. Our results suggest that the CHIKV outbreak in the Americas could potentially spread throughout Ae. aegypti- and Ae. albopictus-infested regions of the Americas however with a limited risk of spillovers in Ae. albopictus-infested regions in Europe. These data will be useful for adapting vector control strategies and epidemiological surveillance.
Palavras-Chave: Biological surveys; Barriers; Pest control; Genotypes; Hosts; Aquatic insects; Disease transmission; Public health; Temperature effects; Data processing; Biting; Travellers; Vectors; Saliva; Infection; Aedes aegypti; Chikungunya virus; Aedes albopictus
Imprenta: Plos Neglected Tropical Diseases, v. 9, n. 5, 2015.
Descritores: Aedes aegypti - Virus ; Aedes aegypti - Transmission ; Aedes aegypti - Public health
Data de publicação: 2015
