Arterial hypertension and skin allergy are risk factors for progression from dengue to dengue hemorrhagic fever: a case control study
Autor(es): Teixeira, Maria Gloria; Paixao, Enny S.; Costa, Maria da Conceicao N.; Cunha, Rivaldo V.; Pamplona, Luciano; Dias, Juarez P.; Figueiredo, Camila A.; Figueiredo, Maria Aparecida A.; Blanton, Ronald; Morato, Vanessa; Barreto, Mauricio L.; Rodrigues, Laura C.
Resumo: Dengue is a virus disease that has already reached more than 100 countries worldwide, transmitted by Aedes mosquitos, mainly Aedes aegypti. It is estimated that annually nearly 96 million symptomatic cases and about 22,000 deaths occur. This virus most often manifests itself in the form of Dengue Fever (DF), which in some cases progresses to severe forms, also called Dengue Hemorrhagic Fever (DHF). However, the current knowledge does not allow early prediction of which cases of DF will progress to DHF. But it is important to know the factors Involved in this process so that physicians may intervene early to prevent progression and avoid deaths. One of the proposed explanations is that preexisting comorbidities would increase the risk of progression from DF to DHF. This study showed that cases of DF associated with hypertension or skin allergy are more likely to progress to DHF. Monitoring and early appropriate clinical management of these cases can save lives.
Palavras-Chave: Dengue fever; Epidemics; Physicians; Hypertension; Public health; Pathogenesis; Immunology; Risk factors; Hypotheses; Chronic illnesses; Mortality; Diabetes
Imprenta: Plos Neglected Tropical Diseases, v. 9, n. 5, 2015.
Descritores: Aedes aegypti - Virus ; Aedes aegypti - Transmission ; Aedes aegypti - Dengue ; Aedes aegypti - Epidemiology
Data de publicação: 2015
