Antifungal and larvicidal compounds from the root bark of Cordia alliodora

Autor(es): Ioset, Jean-Robert; Marston, Andrew; Gupta, Mahabir P.; Hostettmann, Kurt


Resumo: Two new natural products, a phenylpropanoid derivative characterized as 1-(3'-methoxypropanoyl)-2,4,5-trimethoxybenzene (1) and a prenylated hydroquinone, 2-(2Z)-(3-hydroxy-3,7-dimethylocta-2,6-dienyl)-1,4-benzenediol (2), have been isolated from the root bark of Cordia alliodora. Both compounds exhibited antifungal properties against the phytopathogenic mold Cladosporium cucumerinum. The phenylpropanoid derivative (1), whose structure is closely related to *b-asarone, also demonstrated a marked activity against larvae of the yellow-fever-transmitting mosquito Aedes aegypti.


Palavras-Chave: Molecular structure; Pharmacology; Aquatic drugs; Pesticides; Fungicides; Larvae; Pest control; Metabolites; Hydroquinone; Molds; Roots; Bark


Imprenta: Journal of Natural Products, v. 63, n. 3, p. 424-426, 2000.


Descritores: Aedes aegypti - Molecular Structure


Data de publicação: 2000