On the Treatment of Airline Travelers in Mathematical Models

Autor(es): Johansson, Michael A.; Arana-Vizcarrondo, Neysari; Biggerstaff, Brad J.; Staples, J. Erin; Gallagher, Nancy; Marano, Nina


Resumo: The global spread of infectious diseases is facilitated by the ability of infected humans to travel thousands of miles in short time spans, rapidly transporting pathogens to distant locations. Mathematical models of the actual and potential spread of specific pathogens can assist public health planning in the case of such an event. Models should generally be parsimonious, but must consider all potentially important components of the system to the greatest extent possible. We demonstrate and discuss important assumptions relative to the parameterization and structural treatment of airline travel in mathematical models. Among other findings, we show that the most common structural treatment of travelers leads to underestimation of the speed of spread and that connecting travel is critical to a realistic spread pattern. Models involving travelers can be improved significantly by relatively simple structural changes but also may require further attention to details of parameterization.


Palavras-Chave: Aedes aegypti diptera; Infectious diseases; Pandemic influenza; United States; Air travel; Hong Kong; Spread; Surveillance; Dengue; Impact


Imprenta: Plos One, v. 6, n. 7, p. -, 2011


Identificador do objeto digital: 10.1371/journal.pone.0022151


Descritores: Aedes aegypti - Infectious diseases ; Aedes aegypti - Public health


Data de publicação: 2011