Evolution of the achaete-scute complex in insects: convergent duplication of proneural genes
Autor(es): Negre, Barbara; Simpson, Pat
Resumo: Proneural genes encode transcriptional activators of the basic Helix-loop-helix class that are involved in neuronal specification and differentiation. We have used the recent availability of genome sequences of multiple distant insect species to study the evolution of a family of proneural genes, the achaete-scute genes, and to examine their genomic organization and evolution. We document independent evolution of multiple copies of achaete-scute homologues and argue that this might have contributed to morphological diversity in Diptera and Lepidoptera.
Palavras-Chave: Neural Precursor Specification; Bombyx-Mori; Tribolium-Castaneum; Genome Sequence; Aedes-Aegypti; Drosophila; Reveals; Expression; Conservation; Divergence
Imprenta: Trends in Genetics, v. 25, n. 4, p. 147-152, 2009
Identificador do objeto digital: 10.1016/j.tig.2009.02.001
Descritores: Aedes aegypti - Genome
Data de publicação: 2009
