Emodin isolated from Cassia obtusifolia (Leguminosae) seed shows larvicidal activity against three mosquito species
Autor(es): Yang, YC; Lim, MY; Lee, HS
Resumo: Mosquito larvicidal activity of Cassia obtusifolia (Leguminosae) seed-derived materials against the fourth-instar larvae of Aedes aegypti, Aedes togoi, and Culex pipiens pallens was examined. The chloroform fraction of C. obtusifolia extract showed a strong larvicidal activity of 100% mortality at 25 mg/L. The biologically active component of C. obtusifolia seeds was characterized as emodin by spectroscopic analyses. The LC50 values of emodin were 1.4, 1.9, and 2.2 mg/L against C. pipiens pallens, A. aegypti, and A. togoi, respectively. Pirimiphos-methyl acts as a positive control directly compared to emodin. Pirimiphos-methyl was a much more potent mosquito larvicide than emodin. Nonetheless, emodin may be useful as a lead compound and new agent for a naturally occurring mosquito larvicidal agent. In tests with hydroxyanthraquinones, no activity was observed with alizarin, danthron, and quinizarin, but purpurin has an apparent LC50 value of similar to19.6 mg/L against A. aegypti.
Palavras-Chave: Aedes aegypti; Cassia obtusifolia; Culex pipiens pallens; Emodin; Mosquito larvicidal activity
Imprenta: Journal of Agricultural and Food Chemistry, v. 51, n. 26, p. 7629-7631, 2003
Identificador do objeto digital: 10.1021/jf034727t
Descritores: Aedes aegypti - Larvicide
Data de publicação: 2003
