Analysis of genetic relatedness between populations of Aedes aegypti from different geographic regions of Sao Paulo State, Brazil.

Autor(es): dos Santos, Veruska Marques; Macoris, Maria de Lourdes da Graca; Andrighetti, Maria Teresa Macoris; Avila, Priscilla Elisangela; Kirchgatter, Karin


Resumo: RAPD markers have been used for the analysis of genetic differentiation of Aedes aegypti, because they allow the study of genetic relationships among populations. The aim of this study was to identify populations in different geographic regions of the Sao Paulo State in order to understand the infestation pattern of A. aegypti. The dendrogram constructed with the combined data set of the RAPD patterns showed that the mosquitoes were segregated into two major clusters. Mosquitoes from the Western region of the Sao Paulo State constituted one cluster and the other was composed of mosquitoes from a laboratory strain and from a coastal city, where the largest Latin American port is located. These data are in agreement with the report on the infestation in the Sao Paulo State. The genetic proximity was greater between mosquitoes whose geographic origin was closer. However, mosquitoes from the coastal city were genetically closer to laboratory-reared mosquitoes than to field-collected mosquitoes from the Sao Paulo State. The origin of the infestation in this place remains unclear, but certainly it is related to mosquitoes of origins different from those that infested the West and North region of the State in the 80's.


Palavras-Chave: Aedes aegypti; RAPD-PCR; Mosquito; Random PCR; Dengue vectors; Population genetics


Imprenta: Revista do Instituto de Medicina Tropical de Sao Paulo, v. 45, n. 2, p. 99-101, 2003


Identificador do objeto digital: 10.1590/S0036-46652003000200009


Descritores: Aedes aegypti - DNA ; Aedes aegypti - Public health


Data de publicação: 2003