Advances in Research of Odorant Receptor Proteins of Mosquitoes
Autor(es): Dai Yu-Hua; Zhao Zhong-Yi; Cheng Peng; Liu Li-Juan; Gong Mao-Qing
Resumo: Mosquitoes are one of the most important vectors for transmitting diseases such as malaria, dengue fever and yellow fever. In mosquitoes, the olfactory system plays a crucial role in many types of behavior, including nectar feeding, host preference selection and oviposition. Odorant receptors ( ORs) are comprised of highly variable odorant-binding subunits associated with one conserved co-receptor. They are potential molecular targets for the development of novel mosquito attractants and repellents. ORs have been identified in the malaria mosquito, Anopheles gambiae, and in the yellow fever mosquito, Aedes aegypti. This review enclosed the lately research progress of ORs, including the characteristics of structure, expression regulation and physiological function. Moreover, a highly conserved, broadly expressed olfactory receptor Or83b were summarized in the article. The relationship between OR with the development of mosquito repellents was also involved in the present paper.
Palavras-Chave: Fun?Æo da expressÆo; Repelente - Receptor olfativo
Imprenta: Jishengchong Yu Yixue Kunchong Xuebao, v. 21, n. 1, p. 59-64, 2014
Identificador do objeto digital: 10.3969/j.issn.1005-0507.2014.01.009
Descritores: Aedes aegypti - Biochemistry ; Aedes aegypti - Repellent ; Aedes aegypti - Public health
Data de publicação: 2014