Advances in dissecting mosquito innate immune responses to arbovirus infection
Autor(es): Fragkoudis, Rennos; Attarzadeh-Yazdi, Ghassem; Nash, Anthony A.; Fazakerley, John K.; Kohl, Alain
Resumo: Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signal ling pathways, and cell death/apoptosis.
Palavras-Chave: Semliki forest - Virus; West nile - Virus; Aedes albopictus - Cells; Double stranded -RNA; Vesicular stomatitis - Virus; Vector anopheles - Gambiae; La-Crosse virus; Sindbis - Virus; Antiviral immunity; Drosophila - Melanogaster
Imprenta: Journal of General Virology, v. 90, p. 2061-2072, 2009
Identificador do objeto digital: 10.1099/vir.0.013201-0
Descritores: Aedes aegypti - Immune response ; Aedes aegypti - Molecular structure ; Aedes aegypti - Infectious diseases ; Aedes aegypti - Dengue ; Aedes aegypti - Public health
Data de publicação: 2009
