Inquiry into a fatal case of yellow fever in Cote d'lvoire in 1999

Autor(es): Akoua-Koffi, C; Diarrassouba, S; Benie, VB; Ngbichi, JM; Bozoua, T; Bosson, A; Akran, V; Carnevale, P; Ehouman, A


Resumo: Cote d'Ivoire is an endemic country for yellow fever but no case was officially notified in recent years. In July 1999, however one fatal case was reported, A German citizen was infected in the national park of Comoe, in the north eastern area of the country, In order to evaluate the extent of amaril virus circulation and the risk for local people, a virological entomological and epidemiological investigation logical investigation was carried out by the ministry of health, the OCCGE, the Cote d'Ivoire Pasteur Institute (IPCI) and the World Health Organisation in the area where the fatal case had been staying. 18 suspected and 24 confirmed mosquito catchers were identified by interview and a blood specimen was collected from each of them. In addition, 159 batches of mosquitoes from which 94 batches of potential vectors were collected; among the suspected cases, 22% were immunised against yellow fever Serological and virological analyses were made at IPCI and the Paris Pasteur Institute by ELISA technique and isolation on cells cultures and newborn mice. All the suspicious sera and 87,5% of the catchers were positive for IgG anti-amaril virus. One catchers serum was positive for IgM anti-amaril virus. 11 suspected sera were positive for IgG anti-dengue virus with 1 positive for IgM. 1 strain of amaril virus and 3 strains of Zika virus were isolated from mosquitoes at IPCI and confirmed by CRORA in Dakar These results indicated that there is a yellow fever and dengue virus are prevalent among the human and vector populations in the study area. Preventive measures must be adopted to protect human beings at risk for amaril infection.


Palavras-Chave: Yellow fever; Dengue; Inquiry; Zika virus; Cote d'Ivoire; Ivory Coast; Sub-Saharan Africa; Divoire


Imprenta: Bulletin de la Societe de Pathologie Exotique, v. 94, n. 3, p. 227-230, 2001.


Descritores: Zika virus - Cell ; Zika virus - Dengue ; Zika virus - Zika fever


Data de publicação: 2001