Possible association between recent migration and hospitalisation for dengue in an urban population: a prospective case-control study in northern Vietnam.

Autor(es): Tsuzuki Ataru; Duoc Vu Trong; Sunahara Toshihiko; Suzuki Motoi; Le Nguyen Hoang; Higa Yukiko; Yoshida Lay-Myint; Hasebe Futoshi; Phong Tran Vu; Minakawa Noboru

Resumo: A prospective case-control study was conducted in urban districts in Hanoi, northern Vietnam to evaluate the effect of migration on the risk of hospitalisation for dengue in a Vietnamese urban population. We enrolled laboratory-confirmed dengue patients aged ? 18 years who were hospitalised in local hospitals in November and December 2010. Four neighbourhood-matched controls for each case were recruited within a week of hospitalisation. Sociodemographic data were collected by interviews, and the number of immature and adult mosquitoes within household premises was counted by entomological survey. Matched-pair analyses were conducted using conditional logistic regression models. Among 43 cases and 168 controls, 84% and 83% were migrants from rural areas, respectively. Although statistical significance was marginal, recent migration (residing in study area for ? 5 years) independently increased the risk of hospitalisation for dengue compared with inhabitants after controlling for potential confounders (adjusted odds ratio [aOR] = 3.78; 95% confidence interval [CI] = 0.99-14.27), whereas longer-term migration (residing in study area for ? 6 years) did not change the risk (aOR = 1.1; 95% CI = 0.30-4.05). Younger age (18-34 years) (aOR = 7.26; 95% CI = 2.39-22.06) and higher adult Aedes aegypti infestation level within household premises (aOR = 9.25; 95% CI = 1.68-51.09) were also independently associated with hospitalisation for dengue. Recent migration from rural areas seems to increase the risk of hospitalisation for dengue in urban populations in endemic areas. Further research including cohort study should be done to confirm the impact of migration on the risk of dengue in urban areas.

Imprenta: Tropical Biomedicine, v. 31, n. 4, p. 698-708, 2014

Descritores: Aedes aegypti - Infectious diseases ; Aedes aegypti - Viral infections ; Aedes aegypti - Dengue ; Aedes aegypti - Epidemiology ; Aedes aegypti - Public health

Data de publicação: 2014