Passive transfer between experimental animals of hypersensitivity to Aedes aegypti bites.
Autor(es): Allen J R
Resumo: Attempts were made to demonstrate passive tranfer between experimental animals of immediate-type hypersensitivity to Aedes aegypti bites. Seven out of eight guinea pig recipients of sera from donors sensitized by oral secretion and adjuvant showed immediate-type skin reactions when tested by A. aegypti bite. No passive transfer was demonstrated with sera from donors sensitized by A. aegypti bites, nor was transfer successful when rabbits were used as recipients. Spleen cells from donors sensitized by oral secretion and adjuvant were used in experiments to demonstrate passive transfer of delayed-type hypersensitivity to A. aegypti bite. Successful transfers were obtained with guinea pig recipients. The cells were apparently capable of transferring both immediate- and delayed-type hypersensitivities. No success was achieved with rabbit recipients.
Imprenta: Experimental Parasitology, v. 19, n. 1, p. 132-137, 1966
Identificador do objeto digital: 10.1016/0014-4894(66)90061-0
Descritores: Aedes aegypti - Pathogenesis ; Aedes aegypti - Immunology
Data de publicação: 1966