Oral susceptibility of Aedes aegypti (Diptera: Culicidae) from Senegal for dengue serotypes 1 and 3 viruses.
Autor(es): Gaye Alioune; Faye Oumar; Diagne Cheikh T; Faye Ousmane; Diallo Diawo; Weaver Scott C; Sall Amadou A; Diallo Mawlouth
Resumo: To investigate the potential for domestic and wild populations of Aedes aegypti from Dakar and Kedougou to develop a disseminated infection after exposure to DENV-3 and DENV-1. We have exposed sylvatic and urban population of Ae. aegypti from Senegal to bloomeals containing dengue serotype 1 and 3. At different incubation period, individual mosquito legs/wings and bodies were tested for virus presence using real time RT-PCR to estimate the infection and dissemination rates. The data indicated low susceptibility to DENV-3 (infection: 2.4-15.2%, and dissemination rates: 0-8.3%) and higher susceptibility to DENV-1 (infection and dissemination rates up to 50%). Aedes aegypti from Senegal seem able to develop a disseminated infection of DENV-1 and DENV-3. Further studies are needed to test their ability to transmit the two serotypes.
Palavras-Chave: Aedes aegypti; Dakar; Kedougou; Senegal; Oral susceptibility; Dengue serotypes 1 and 3
Imprenta: Tropical Medicine & International Health, v. 19, n. 11, p. 1355-1359, 2014
Identificador do objeto digital: 10.1111/tmi.12373.
Descritores: Aedes aegypti - Flaviviridae ; Aedes aegypti - Pathogenesis ; Aedes aegypti - Viral infections ; Aedes aegypti - Real Time PCR ; Aedes aegypti - RT-PCR ; Aedes aegypti - virus ; Aedes aegypti - Transmission ; Aedes aegypti - Dengue ; Aedes aegypti - Public health
Data de publicação: 2014