Notes from the Field: Evidence of Zika Virus Infection in Brain and Placental Tissues from Two Congenitally Infected Newborns and Two Fetal Losses - Brazil, 2015.

Autor(es): Martines Roosecelis Brasil; Bhatnagar Julu; Keating M Kelly; Silva-Flannery Luciana; Muehlenbachs Atis; Gary Joy; Goldsmith Cynthia; Hale Gillian; Ritter Jana; Rollin Dominique; Shieh Wun-Ju; Luz Kleber G; Ramos Ana Maria de Oliveira; Davi Helaine Pompeia Freire; Kleber de Oliveria Wanderson; Lanciotti Robert; Lambert Amy; Zaki Sherif

Resumo: Zika virus is a mosquito-borne flavivirus that is related to dengue virus and transmitted primarily by Aedes aegypti mosquitoes, with humans acting as the principal amplifying host during outbreaks. Zika virus was first reported in Brazil in May 2015 (1). By February 9, 2016, local transmission of infection had been reported in 26 countries or territories in the Americas.* Infection is usually asymptomatic, and, when symptoms are present, typically results in mild and self-limited illness with symptoms including fever, rash, arthralgia, and conjunctivitis. However, a surge in the number of children born with microcephaly was noted in regions of Brazil with a high prevalence of suspected Zika virus disease cases. More than 4,700 suspected cases of microcephaly were reported from mid-2015 through January 2016, although additional investigations might eventually result in a revised lower number (2). In response, the Brazil Ministry of Health established a task force to further investigate possible connections between the virus and brain anomalies in infants (3).

Imprenta: Morbidity and Mortality Weekly Report, v. 65, n. 6, p. 159-160, 2016

Identificador do objeto digital: 10.15585/mmwr.mm6506e1.

Descritores: Aedes aegypti - virus ; Aedes aegypti - Transmission ; Aedes aegypti - Dengue ; Aedes aegypti - Microcephaly ; Aedes aegypti - Zika fever

Data de publicação: 2016