Autor(es): do Nascimento Jeferson C; David Jorge M; Barbosa Luiz C A; de Paula Vanderlucia F; Demuner Antonio J; David Juceni P; Conserva Lucia M; Ferreira Jésu C; Guimar?es Elsie F

Resumo: Volatile oils from fresh roots, stems, leaves and seeds of Piper klotzschianum (Piperaceae) were obtained by hydrodistillation and analysed by GC-FID and GC-MS. In total, 25 components, representing more than 95% of the examined oils, were identified. The essential oils were evaluated against Artemia salina Leach nauplii and fourth-instar Aedes aegypti larvae. The major chemical constituents that were identified from various parts of this plant were 1-butyl-3,4-methylenedioxybenzene and 2,4,5-trimethoxy-1-propenylbenzene in the root, 1-butyl-3,4-methylenedioxybenzene in the stems and leaves and 1-butyl-3,4-methylenedioxybenzene, limonene and ?-phellandrene in the seeds. The biological activities of these essential oils generally exhibited high toxicity against A. salina, with LC50 values that ranged from 7.06 to 15.43 µg mL(-1), and significant larvicidal activity against fourth-instar A. aegypti larvae was observed in the essential oils from the seeds (LC50 of 13.27 µg mL(-1)) and roots (LC50 of 10.0 µg mL(-1)) of the plant. The present study indicates that both essential oil of P. klotzsdhianum and the isolate 1-butyl-3,4-methylenedioxybenzene are potential resources for A. aegypti larva control. This is the first report of the biological activities of the oil and isolated compound.

Palavras-Chave: Piper klotzschianum; Piperaceae Aedes aegypti; Larvicidal activity cytotoxic activities

Imprenta: Pest Management Science, v. 69, n. 11, p. 1267-1271, 2013

Identificador do objeto digital: 10.1002/ps.3495

Descritores: Aedes aegypti - Molecular Structure ; Aedes aegypti - Public health

Data de publicação: 2013