Homologous interference in Aedes aegypti cell cultures infected with Sindbis virus.

Autor(es): Peleg J; Stollar V


Resumo: The establishment of persistent infection by Sindbis virus inAedes aegypti cell cultures is independent of the initial multiplicity of infection. Persistently infected cultures yield a small plaque-forming virus mutant, SV-S, which interferes with the growth of the wild type Sindbis virus, SV-W, but not with Eastern equine encephalitis virus, another group A togavirus. The interfering capacity of SV-S was demonstrated in BHK-21 and KB cells as well as in mosquito cells


Palavras-Chave: Cell culture; Infectious disease; Encephalitis; Persistent infection; Encephalitis virus


Imprenta: Archiv fu?r die gesamte Virusforschung, v. 45, n. 4, p. 309-318, 1974


Descritores: Aedes aegypti - Cell ; Aedes aegypti - Pathogenesis ; Aedes aegypti - Proteins ; Aedes aegypti - Serology ; Aedes aegypti - Viral infections ; Aedes aegypti - Virus ; Aedes aegypti - Immunology


Data de publicação: 1974