Gustatory receptor expression in the labella and tarsi of Aedes aegypti.

Autor(es): Sparks Jackson T; Vinyard Bryan T; Dickens Joseph C

Resumo: The yellow-fever mosquito, Aedes aegypti, infects a growing number of people every year with dengue, yellow fever and chikungunya viruses. Contact chemoreception in mosquitoes influences a number of behaviors including host-selection, oviposition and feeding. While these behaviors are in many instances well documented, the molecular mechanisms mediating them are not well understood. Here we report the results of sequencing total messenger RNA in the labella and tarsi of both male and female Ae. aegypti to reveal Gustatory Receptor (GR) gene expression profiles in these major gustatory appendages. Gene expression levels in each tissue were verified by RT-qPCR. We discuss potential functions for the GRs revealed here by considering homologous GRs in other insects. Specific GRs provide molecular targets for modification of gustatory-mediated behaviors in this important disease vector.

Palavras-Chave: Gustatory receptor; Taste; Aedes aegypti; Labella Tarsi

Imprenta: Insect Biochemistry and Molecular Biology, v. 43, n. 12, p. 1161-1171, 2013

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Descritores: Aedes aegypti - Cell ; Aedes aegypti - Pathogenesis ; Aedes aegypti - Proteins ; Aedes aegypti - RNA ; Aedes aegypti - Viral infections ; Aedes aegypti - Virus ; Aedes aegypti - Transmission ; Aedes aegypti - Chikungunya Fever ; Aedes aegypti - Dengue ; Aedes aegypti - Public health

Data de publicação: 2013