Experimental infection of Aedes aegypti and Aedes albopictus with dengue viruses

Autor(es): Whitehead R H; Yuill T M; Gould D J; Simasathien P

Resumo: The susceptibility of two Aedes (Stegomyia) species, Ae. aegypti and Ae. albopictus, to infection with dengue virus was assessed using both natural feeding on a viraemic gibbon and a membrane feeding technique. Both species were highly susceptible to dengue virus infection. It was found that both species were more sensitive than the LLC-MK2 cell plaque assay system used in detecting viraemia in a gibbon infected with a low tissue culture passage strain of dengue-2 virus. However, the same strain passaged in LLC-MK2 cells failed to infect either species when the mosquitoes were fed upon a suspension of this virus. Both species were infected readily when fed upon a suspension of a mouse adapted strain of dengue-2 virus.

Imprenta: Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 65, n. 5, p. 661-667, 1971

Identificador do objeto digital: https://doi.org/10.1016/0035-9203(71)90051-4

Descritores: Aedes aegypti - Flaviviridae ; Aedes aegypti - Pathogenesis ; Aedes aegypti - virus ; Aedes aegypti - Dengue ; Aedes aegypti - Public health

Data de publicação: 1971