Evaluation of seed extracts from plants found in the Caatinga biome for the control of Aedes aegypti
Autor(es): Barbosa Patrícia Batista Barra Medeiros; de Oliveira Julliete Medeiros; Chagas Juliana Macêdo; Rabelo Luciana Maria Araujo; de Medeiros Guilherme Fulgêncio; Giodani Raquel Brant; da Silva Elizeu Antunes; Uchôa Adriana Ferreira; de Fátima de Freire Melo Ximenes Maria
Resumo: Dengue fever, currently the most important arbovirus, is transmitted by the bite of the Aedes aegypti mosquito. Given the absence of a prophylactic vaccine, the disease can only be controlled by combating the vector insect. However, increasing reports of resistance and environmental damage caused by insecticides have led to the urgent search for new safer alternatives. In this regard, plants stand out as a source of easy-to-obtain biodegradable insecticide molecules. Twenty (20) plant seed extracts from the Caatinga, an exclusively Brazilian biome, were prepared. Sodium phosphate (50 mM, pH 8.0) was used as extractor. The extracts were used in bioassays and submitted to partial characterisation. A Probit analysis of insecticides was carried out, and intergroup differences were verified by the Student's t test and ANOVA. All the extracts exhibited larvicidal and ovipositional deterrence activity. The extracts of Amburana cearenses, Piptadenia viridiflora, Erythrina velutina, Myracrodruon urundeuva and Schinopsis brasiliensis were also pupicides, while the extracts of P. viridiflora, E. velutina, A. cearenses, Anadenanthera colubrina, Diocleia grandiflora, Bauhinia cheilantha, Senna spectabilis, Caesalpinia pyramidalis, Mimosa regnelli and Genipa americana displayed adulticidal activity. Egg laying was compromised when females were fed extracts of Ricinus communis, Croton sonderianus and S. brasiliensis. At least two proteins with insecticidal activity were found in all the extracts. Phenol compounds were identified in all the extracts and flavonoids, triterpenes or alkaloids in 14 of them. The results show the potential of plant seed extracts from the Caatinga as a source of active molecules against A. aegypti mosquitos.
Imprenta: Parasitology Research, v. 113, n. 10, p. 3565-3580, 2014
Descritores: Aedes aegypti - Arbovirus ; Aedes aegypti - Biochemistry ; Aedes aegypti - Cell ; Aedes aegypti - Proteins ; Aedes aegypti - Vaccine ; Aedes aegypti - Dengue
Data de publicação: 2014
