Guillain-Barré syndrome surveillance during National Influenza Vaccination Campaign, New York, U.S.A., 2009.

Autor(es): Giambrone Gregory P.; Zansky Shelley M.; Eidson Millicent; Duncan Pamela G.; McNutt Louise-Anne; Birkhead Guthrie S.


Resumo: The New York State Department of Health (NYSDOH) collected information about hospitalized patients with Guillain-Barré syndrome (GBS) during October 2009-May 2010, statewide (excluding New York City), to examine a possible relationship with influenza A(H1N1)pdm09 vaccination. NYSDOH established a Clinical Network of neurologists and 150 hospital neurology units. Hospital discharge data from the Statewide Planning and Research Cooperative System (SPARCS) were used to evaluate completeness of reporting from the Clinical Network. A total of 140 confirmed or probable GBS cases were identified: 81 (58%) from both systems, 10 (7%) from Clinical Network only, and 49 (35%) from SPARCS-only. Capture-recapture methods estimated that 6 cases might have been missed by both systems. Clinical Network median reporting time was 12 days versus 131 days for SPARCS. In public health emergencies in New York State, a Clinical Network may provide timely data, but in our study such data were less complete than traditional hospital discharge data.


Palavras-Chave: GBS, Guillain-Barré syndrome, New York, influenza A(H1N1) 2009 monovalent vaccine, pandemic H1N1 2009 influenza virus, vaccination campaign, viruses


Imprenta: Emerging Infectious Diseases, v. 19, n. 12, p. 1956-1962, 2013


Identificador do objeto digital: 10.3201/eid1912.130643


Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Virus ; Guillain-Barre Syndrome - Vaccine ; Guillain-Barre Syndrome - Epidemiology ; Guillain-Barre Syndrome - Immunology ; Guillain-Barre Syndrome - Public health


Data de publicação: 2013