Guillain-Barré syndrome mimics primary biliary cirrhosis-related myopathy.
Autor(es): Munday William R; DiCapua Daniel; Vortmeyer Alexander; Gomez Jose Luis
Resumo: Guillain-Barré syndrome (GBS) is an immune-mediated disorder characterized by acute polyneuropathy, ascending paralysis and post infectious polyneuritis. Two-thirds of patients present with a history of recent upper respiratory tract or gastrointestinal infection. The clinical history, neurologic examination and laboratory assessment allow for a straightforward diagnosis in the majority of cases. However, primary biliary cirrhosis (PBC) is known to cause clinically detectable muscular weakness. It is therefore critical to differentiate between PBC-associated muscular weakness and GBS-induced paralysis. Here, we report a patient with a longstanding history of PBC who developed progressive weakness and respiratory failure due to GBS, which clinically mimicked PBC myopathy. This is the first reported association between GBS and PBC.
Imprenta: Oxford Medical Case Reports, v. 2015, n. 4, p. 272-5, 2015
Identificador do objeto digital: 10.1093/omcr/omv033
Descritores: Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Clinical examination
Data de publicação: 2015
