Guillain-Barré syndrome in childhood: natural course and efficacy of plasmapheresis.

Autor(es): Jansen P. W.; Perkin R. M.; Ashwal S.

Resumo: Eight children with Guillain-Barré syndrome were treated with plasmapheresis. Retrospective comparisons were made with 11 historic control patients. Eight children required mechanical ventilation, 4 of whom were in the plasmapheresis group. One week after the last plasmapheresis treatment, patients receiving plasmapheresis within 7 days of symptom onset had improved by one Guillain-Barré syndrome score. Discharge Guillain-Barré syndrome scores were significantly lower for those receiving plasmapheresis (P < .05). Patients in the plasmapheresis group had a decrease in the number of days of mechanical ventilation, time until motor recovery, and overall cost. Our results are consistent with published literature and indicate that plasmapheresis for childhood Guillain-Barré syndrome is a safe and effective treatment to shorten the time to recovery.

Imprenta: Pediatric Neurology, v. 9, n. 1, p. 16-20, 1993

Identificador do objeto digital: 10.1016/0887-8994(93)90004-V

Descritores: Guillain-Barre Syndrome - Public health

Data de publicação: 1993