Guillain-Barré syndrome associated with resistant cytomegalovirus infection after face transplantation.
Autor(es): Alhefzi M.; Aycart M. A.; Bueno E. M.; Kueckelhaus M.; Fischer S.; Snook R. J.; Sharfuddin A. A.; Hadad I.; Malla P.; Amato A. A.; Marty F. M.; Pomahac B.
Resumo: A 39-year-old male, who received a facial allograft (cytomegalovirus [CMV] donor-seropositive, recipient-seronegative), developed multidrug-resistant CMV infection despite valGCV prophylaxis (900 mg/day) 6 months post transplantation. Lower extremity weakness with upper and lower extremity paresthesias developed progressively 11 months post-transplantation, coinciding with immune control of CMV. An axonal form of Guillain-Barré syndrome was diagnosed, based on electrophysiological evidence of a generalized, non-length- dependent, sensorimotor axonal polyneuropathy. Treatment with intravenous immunoglobulin led to complete recovery without recurrence after 6 months. This article is protected by copyright. All rights reserved.
Palavras-Chave: Guillian-Barré syndrome, cytomegalovirus, face transplantation, peripheral neuropathy, vascularized composite allotransplantation
Imprenta: Transplant Infectious Disease, 2016
Identificador do objeto digital: 10.1111/tid.12516
Descritores: Guillain-Barre Syndrome - Infectious diseases
Data de publicação: 2016
