Guillain-Barré syndrome associated with IgM anti-GM1 antibody following Campylobacter jejuni enteritis.
Autor(es)Sugita K.; Ishii M.; Takanashi J.; Niimi H.; Yuki N.
ResumoWe report a 4-year-old girl diagnosed as having Guillain-Barré syndrome after infection by Penner serotype 19 of Campylobacter jejuni. The patient had the HLA-B35 antigen. Neurological examination revealed distal-dominant weakness and intact sensation. Serial electrophysiological studies indicated that the predominant process was axonal degeneration involving motor nerves. An enzyme-linked immunosorbent assay revealed the presence of high titres of serum IgM antibodies to gangliosides GM1 and GM2. The IgM auto-antibody titres decreased concurrently with the clinical course of the illness and no switching from IgM to IgG secretion took place.
ImprentaEuropean Journal of Pediatrics, v. 153, n. 3, p. 181-183, 1994
Identificador do Objeto Digital10.1007/BF01958981
DescritoresGuillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Clinical examination ; Guillain-Barre Syndrome - Immunology;
Data de Publicação:1994
