Guillain-Barré syndrome after varicella-zoster infection. Report of two cases.

Autor(es): Sanders E. A.; Peters A. C.; Gratana J. W.; Hughes R. A.

Resumo: Two patients developed Guillain-Barré syndrome after varicella-zoster infection; a 4-year-old boy after chickenpox and a 74-year-old man after shingles. Both had decreased CD8-positive lymphocytes in the blood during the course of their illness. These cases and others reported in the literature suggest that varicella-zoster infection is a significant but rare trigger factor of Guillain-Barré syndrome. An alteration in the balance of helper and suppressor lymphocytes may be an important pathogenetic mechanism.

Imprenta: Journal of Neurology, v. 234, n. 6, p. 437-439, 1987

Identificador do objeto digital: 10.1007/BF00314094

Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Immunology

Data de publicação: 1987