Getting closer to patients: the INCAT Overall Disability Sum Score relates better to patients' own clinical judgement in immune-mediated polyneuropathies.
Autor(es): Merkies I. S. J.; Schmitz P I. M.
Resumo: To determine which widely used disability measure in Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP) shows the strongest association with patients' rating scores. Five disability scales and the Medical Outcomes Study 36-Item Short Form Health Survey (SF-36) were assessed serially in 20 patients with newly diagnosed GBS (n = 7) or CIDP (n = 13). Also at each visit, the patient's condition was self-assessed as being worse, unchanged or better. Longitudinal regressions were carried out to determine the association between disability scales (independent variables) and SF-36 and patients' rating scores (dependent variables). Higher associations with the SF-36 were found in the Overall Disability Sum Score (ODSS) than other disability measures. A higher correlation with ODSS changes was also found in the rating scores of the patients. In addition to literature findings, higher associations were found between Inflammatory Neuropathy Cause and Treatment Group ODSS and outcome assessed from patients' perceptions in immune-related polyneuropathies than in other commonly used disability scales.
Imprenta: Journal of Neurology, Beurosurgery, and Psychiatry, v. 77, n. 8, p. 970-972, 2006
Identificador do objeto digital: 10.1136/jnnp.2005.076174
Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Public health
Data de publicação: 2006
