Failure of 3,4-diaminopyridine to reverse conduction block in inflammatory demyelinating neuropathies.
Autor(es): Bergin P. S.; Miller D. H.; Hirsch N. P.; Murray N. M.
Resumo: 3,4-Diaminopyridine was administered to 6 patients with inflammatory demyelinating neuropathies in whom partial conduction block was demonstrable. Four had Guillain-Barré syndrome and 2 had chronic inflammatory demyelinating neuropathy. Nerve conduction studies were performed before the administration of a single oral dose of 3,4-diaminopyridine, and at regular intervals thereafter. Neither resolution of conduction block nor clinical benefit were seen.
Imprenta: Annals of Neurology, v. 34, n. 3, p. 406-409, 1993
Identificador do Objeto Digital: 10.1002/ana.410340318
Descritores: Guillain-Barre Syndrome - Proteins
Data de Publicação: 1993