Dysgeusia in a Patient with Guillain-Barré Syndrome Associated with Acute Hepatitis E: A Case Report and Literature Review

Autor(es): Higuchi Masa-Aki,Fukae Jiro,Tsugawa Jun,Ouma Shinji,Takahashi Kazuaki,Mishiro Shunji,Tsuboi Yoshio

Resumo: Guillain-Barré syndrome (GBS) is usually triggered by viral or bacterial infection. In addition, it was recently reported that infection with hepatitis E virus (HEV) also causes GBS. A 49-year-old man presented with acute-onset paralysis in all extremities and dysgeusia during an episode of acute hepatitis. Serological tests showed the presence of anti-HEV IgM antibodies and HEV-RNA in the serum. As an electrophysiological examination showed acute demyelinating polyradiculoneuropathy, the patient was diagnosed as HEV-associated GBS. Following the initiation of treatment with intravenous immunoglobulin, his paralysis and dysgeusia rapidly improved. This case suggests that HEV-associated GBS may rarely be complicated by dysgeusia.

Palavras-Chave: Guillain-Barré syndrome; Hepatitis E; IVIg; Muscle weakness; Dysgeusia

Imprenta: Internal Medicine (Tokyo, Japan), v. 54, n. 12, p. 1543-1546, 2015

Identificador do objeto digital: 10.2169/internalmedicine.54.3506

Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - RNA ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Serological diagnosis ; Guillain-Barre Syndrome - virus ; Guillain-Barre Syndrome - Immunology ; Guillain-Barre Syndrome - Public health

Data de publicação: 2015