Disseminated intravascular large-cell lymphoma with initial presentation mimicking Guillain-Barré syndrome

Autor(es): Jiang Qin Li,Pytel Peter,Rowin Julie

Resumo: We report a patient with intravascular large B-cell lymphoma who initially presented with acute ascending weakness and sensory changes. Electrodiagnostic testing and cerebral spinal fluid (CSF) studies were initially suggestive of a demyelinating polyneuropathy. Further clinical evaluation and testing were consistent with mononeuropathy multiplex. Autopsy revealed disseminated intravascular large-cell lymphoma. Intravascular large-cell lymphoma should be considered in the differential diagnosis of a rapidly evolving neuropathy associated with other organ involvement.

Palavras-Chave: Intravascular large cell lymphoma; Mononeuropathy multiplex; Guillain-Barre´syndrome; Necrotizing vasculitis; Transbronchial biopsy

Imprenta: Muscle & Nerve, v. 42, n. 1, p. 133-136, 2010

Identificador do objeto digital: 10.1002/mus.21648

Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Clinical examination ; Guillain-Barre Syndrome - Public health

Data de publicação: 2010