Dengue infection: neurological manifestations and cerebrospinal fluid (CSF) analysis

Autor(es): Soares C N,Faria L C,Peralta J M,de Freitas M R G,Puccioni-Sohler M


Resumo: Neurological manifestation is considered a rare complication of dengue infection. Neurological and cerebrospinal fluid (CSF) findings of 13 patients with dengue infection were studied. Seven patients had encephalitis, two had myelitis and four showed Guillain-Barré syndrome (GBS). No alteration in CSF was found from 57% of those with encephalitis. Patients with GBS and myelitis showed a CSF-blood barrier dysfunction. The differences in the CSF may be related to the location of the lesion and multiple mechanisms of the disease in the nervous system.


Palavras-Chave: Dengue infection; Neurological manifestations; CSF; Viral encephalitis; Myelitis and Guillain-Barré syndrome


Imprenta: Journal of the Neurological Sciences, v. 249, n. 1, p. 19-24, 2006


Identificador do objeto digital: 10.1016/j.jns.2006.05.068


Descritores: Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Flaviviridae ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Virus ; Guillain-Barre Syndrome - Dengue ; Guillain-Barre Syndrome - Immunology ; Guillain-Barre Syndrome - Public health


Data de publicação: 2006