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Dengue infection: neurological manifestations and cerebrospinal fluid (CSF) analysis

Autor(es)Soares C N,Faria L C,Peralta J M,de Freitas M R G,Puccioni-Sohler M
ResumoNeurological manifestation is considered a rare complication of dengue infection. Neurological and cerebrospinal fluid (CSF) findings of 13 patients with dengue infection were studied. Seven patients had encephalitis, two had myelitis and four showed Guillain-Barré syndrome (GBS). No alteration in CSF was found from 57% of those with encephalitis. Patients with GBS and myelitis showed a CSF-blood barrier dysfunction. The differences in the CSF may be related to the location of the lesion and multiple mechanisms of the disease in the nervous system.
Palavras-ChaveDengue infection; Neurological manifestations; CSF; Viral encephalitis; Myelitis and Guillain-Barré syndrome
ImprentaJournal of the Neurological Sciences, v. 249, n. 1, p. 19-24, 2006
Identificador do Objeto Digital10.1016/j.jns.2006.05.068
DescritoresGuillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Flaviviridae ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Virus ; Guillain-Barre Syndrome - Dengue ; Guillain-Barre Syndrome - Immunology ; Guillain-Barre Syndrome - Public health
Data de Publicação:2006