Delayed facial weakness in Guillain-Barré and Miller Fisher syndromes
Autor(es): Tatsumoto Muneto,Misawa Sonoko,Kokubun Norito,Sekiguchi Yukari,Hirata Koichi,Kuwabara Satoshi,Yuki Nobuhiro
Resumo: Dr. C. Miller Fisher described the appearance of unilateral facial palsy after resolution of ataxia in a patient with the eponymic Miller Fisher syndrome (MFS). However, there have been very few reports of delayed appearance of facial weakness in Guillain-Barré syndrome (GBS) and MFS when the other neurological signs reached nadir or started improving. In this study we reviewed the clinical and laboratory findings of consecutive patients with GBS (n=195) and MFS (n=68). Delayed facial weakness occurred in 12 (6%) GBS and 4 (6%) MFS patients and was unilateral in 5 (42%) GBS and 2 (50%) MFS patients. In those patients with delayed facial weakness, neither limb weakness nor ataxia progressed, and facial weakness disappeared without immunotherapy. Because facial weakness can lead to further morbidity, it would be prudent for clinicians to warn patients of this possibility, although additional immunotherapy is usually not required.
Palavras-Chave: Guillain-Barré syndrome; Miller Fisher syndrome; Acute inflammatory demyelinating polyneuropathy; Acute motor axonal neuropathy; Facial palsy; Facial weakness
Imprenta: Muscle & Nerve, v. 51, n. 6, p. 811-814, 2015
Identificador do objeto digital: 10.1002/mus.24475
Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology ; Guillain-Barre Syndrome - Public health
Data de publicação: 2015
