Defining a treatable cause of erythromelalgia: acute adolescent autoimmune small-fiber axonopathy
Autor(es): Paticoff Joshua,Valovska Assia,Nedeljkovic Srdjan S,Oaklander Anne Louise
Resumo: Conditions described as erythromelalgia" and "erythermalgia" are being formally specified by etiological diagnoses that enable the use of disease-modifying as well as symptomatic treatments. We describe an otherwise healthy 20-year-old man with acute-onset erythromelalgia. Severe bilateral distal limb pain and vasodilation persisted despite the use of many antihyperalgesics. Pathological examination of cutaneous nerve endings revealed severe small-fiber predominant axonopathy. Treatment of his apparent autoimmune polyneuropathy with high dose corticosteroids, 4 days of lidocaine infusion, and a prednisone taper cured him. Similarities to other cases allowed us to tentatively characterize a new treatable cause of erythromelalgia; acute adolescent autoimmune small-fiber axonopathy. In this report we evaluate various options for diagnosis and treatment."
Imprenta: Anesthesia and Analgesia, v. 104, n. 2, p. 438-441, 2007
Identificador do objeto digital: 10.1213/01.ane.0000252965.83347.25
Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis
Data de publicação: 2007
