Cytomegalovirus complement fixation antibody in Guillain-Barré syndrome

Autor(es): Dowling P,Menonna J,Cook S

Resumo: Cytomegalovirus, measles, and adenovirus antibodies were measured in the sera of 92 Guillain-Barré patients and 120 controls. Thirty patients (33 percent) had markedly elevated levels of complement-fixing antibody to cytomegalovirus and in 21, a fourfold or more alteration in titer was demonstrated. Diagnostic falls in titer were seen in most instances and no significant elevation to the other viral agents was found. The serologic findings reported here suggest that cytomegalovirus may be a common agent involved in the pathogenesis of the Guillain-Barré syndrome.

Imprenta: Neurology, v. 27, n. 12, p. 1153-1156, 1977

Identificador do objeto digital: 10.1212/WNL.27.12.1153

Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Serology ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Serology ; Guillain-Barre Syndrome - Virus ; Guillain-Barre Syndrome - Immunology

Data de publicação: 1977