CSF tau protein: a new prognostic marker for Guillain-Barré syndrome

Autor(es): Jin K,Takeda A,Shiga Y,Sato S,Ohnuma A,Nomura H,Arai H,Kusunoki S,Ikeda M,Itoyama Y

Resumo: We measured the CSF tau protein levels in 26 patients with Guillain-Barré syndrome. The levels of the poor outcome group (Hughes grade at 6 months was between II and VI, n = 6) were higher than those of the good outcome group (0 or I, n = 20) (p < 0.0005). The higher levels of CSF tau may reflect axonal degeneration and could predict a poor clinical outcome in Guillain-Barré syndrome.

Imprenta: Neurology, v. 67, n. 8, p. 1470-1472, 2006

Identificador do objeto digital: 10.1212/01.wnl.0000240119.29939.c7

Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology

Data de publicação: 2006