Concurrent Guillain-Barré syndrome and myasthenia gravis: the first case in Taiwan
Autor(es): Kung Sheng-Ling,Su Jang-Ming,Tsai Shin-Jei,Lu Tsong-Ming,Chen Chiu-Mei
Resumo: The concurrent development of Guillain-Barré syndrome (GBS) and myasthenia gravis (MG) is rare. It has been associated with molecular mimicry between infectious agents and self-antigens. Such antibodies may show cross-reactions against both myelin proteins of peripheral nerves and acetylcholine receptors of neuromuscular junctions. Thymoma-associated multi-organ autoimmunity may also play a role in initiating autoimmune process. We present such a case with the concurrent development of GBS and MG.
Palavras-Chave: Guillain-Barré syndrome; Acute inflammatory demyelinating polyradiculoneuropthy; Miller-Fisher syndrome; Polyneuropathy; Thymoma; Myasthenia gravis (MG)
Imprenta: Acta Neurologica Taiwanica, v. 18, n. 3, p. 193-197, 2009
Descritores: Guillain-Barre Syndrome - Biosynthesis ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Autoimmunity ; Guillain-Barre Syndrome - Molecular methods ; Guillain-Barre Syndrome - Molecular screening ; Guillain-Barre Syndrome - Immunology
Data de publicação: 2009
