Coexistence of Guillain-Barré syndrome and Behçet's disease

Autor(es): Shugaiv Erkingul,Kiyat-Atamer Asli,Tüzün Erdem,Deymeer Feza,Oflazer Piraye,Parman Yesim,Akman-Demir Gulsen


Resumo: Behçet's disease (BD) is a multisystemic, recurrent and inflammatory disorder. Neurological involvement is rare and affects mainly the central nervous system (CNS) in the form of brainstem meningoencephalitis or dural sinus thrombosis. Peripheral neuropathy is usually not observed during the course of BD but some reports have shown electrophysiologic evidence of subclinical neuropathy, mononeuritis multiplex and cranial neuropathy in BD patients. The co-occurrence of Guillain-Barré syndrome (GBS), an acute inflammatory demyelinating neuropathy, with other autoimmune or systemic diseases is rare. We present a case of BD with clinical and electrophysiological diagnosis of GBS. The findings of the patient were discussed with reference to literature.


Palavras-Chave: Behçet's disease; Neuro-Behçet; Polyneuropathy; Guillain-Barré syndrome; Autoimmunity


Imprenta: Clinical and Experimental Rheumatology, v. 31, n. 3, supl. 77, p. 88-89, 2013


Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Clinical examination ; Guillain-Barre Syndrome - Immunology


Data de publicação: 2013