Clinical correlation with serum-soluble interleukin-2 receptor levels in Guillain-Barré syndrome

Autor(es): Bansil S,Mithen F A,Cook S D,Sheffet A,Rohowsky-Kochan C

Resumo: In patients with Guillain-Barré syndrome (GBS) soluble interleukin-2 receptor (sIL-2R) levels were elevated compared with those of patients with other neurologic diseases (OND), and of healthy controls. Smaller increases in sIL-2R levels occurred in OND patients compared to healthy subjects. Monitoring of GBS patients clearly demonstrated that decreases in sIL-2R levels correlated with clinical recovery. Thus, T-cell activation may be relevant in the pathogenesis of GBS.

Imprenta: Neurology, v. 41, n. 8, p. 1302-1305, 1991

Identificador do objeto digital: 10.1212/WNL.41.8.1302

Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins

Data de publicação: 1991