Clinical and electrophysiological parameters distinguishing acute-onset chronic inflammatory demyelinating polyneuropathy from acute inflammatory demyelinating polyneuropathy
Autor(es): Dionne Annie,Nicolle Michael W,Hahn Angelika F
Resumo: Up to 16% of chronic inflammatory demyelinating polyneuropathy (CIDP) patients may present acutely. We performed a retrospective chart review on 30 acute inflammatory demyelinating polyneuropathy (AIDP) and 15 acute-onset CIDP (A-CIDP) patients looking for any clinical or electrophysiological parameters that might differentiate AIDP from acutely presenting CIDP. A-CIDP patients were significantly more likely to have prominent sensory signs. They were significantly less likely to have autonomic nervous system involvement, facial weakness, a preceding infectious illness, or need for mechanical ventilation. With regard to electrophysiological features, neither sural-sparing pattern, sensory ratio >1, nor the presence of A-waves was different between the two groups. This study suggests that patients presenting acutely with a demyelinating polyneuropathy and the aforementioned clinical features should be closely monitored as they may be more likely to have CIDP at follow-up.
Palavras-Chave: Acute inflammatory demyelinating polyneuropathy; Chronicinflammatory demyelinating polyneuropathy; Clinical predictors; Electrophysiology; Sural sparing
Imprenta: Muscle & Nerve, v. 41, n. 2, p. 202-207, 2010
Identificador do objeto digital: 10.1002/mus.21480
Descritores: Guillain-Barre Syndrome - Public health
Data de publicação: 2010
