Carcinoma of the uterine cervix with squamous and sebaceous differentiation.

Autor(es): Rizzardi Clara,Perin Tiziana,Schneider Manuela,Rossi Diego,Brollo Alessandro,Melato Mauro,Canzonieri Vincenzo

Resumo: Sebaceous neoplasms, including carcinoma, can exceptionally arise in extracutaneous sites. We present the third known case of carcinoma with sebaceous differentiation in the uterine cervix. Histologic and immunohistochemical features suggested a metaplastic process within an otherwise usual squamous cell carcinoma. We speculate that, by analogy with the skin where the epidermis and the 3 types of adnexa have a common embryologic origin from basal cell layer of the superficial ectoderm, it is possible that endocervical reserve cells, in addition to the well-known capacity of squamous differentiation, retain the potential to give rise to appendages including sebaceous glands.

Imprenta: International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists, v. 28, n. 3, p. 292-295, 2009

Identificador do objeto digital: 10.1097/PGP.0b013e31818d10be

Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Public health

Data de publicação: 2009