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Carcinoma of the uterine cervix with squamous and sebaceous differentiation.

Autor(es)Rizzardi Clara,Perin Tiziana,Schneider Manuela,Rossi Diego,Brollo Alessandro,Melato Mauro,Canzonieri Vincenzo
ResumoSebaceous neoplasms, including carcinoma, can exceptionally arise in extracutaneous sites. We present the third known case of carcinoma with sebaceous differentiation in the uterine cervix. Histologic and immunohistochemical features suggested a metaplastic process within an otherwise usual squamous cell carcinoma. We speculate that, by analogy with the skin where the epidermis and the 3 types of adnexa have a common embryologic origin from basal cell layer of the superficial ectoderm, it is possible that endocervical reserve cells, in addition to the well-known capacity of squamous differentiation, retain the potential to give rise to appendages including sebaceous glands.
ImprentaInternational Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists, v. 28, n. 3, p. 292-295, 2009
Identificador do Objeto Digital10.1097/PGP.0b013e31818d10be
DescritoresGuillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Public health
Data de Publicação:2009