Campylobacter jejuni strains of human and chicken origin are invasive in chickens after oral challenge.
Autor(es): Knudsen Katrine Nørrelund,Bang Dang Duong,Andresen Lars Ole,Madsen Mogens
Resumo: The aim of the study was to evaluate the colonizing ability and the invasive capacity of selected Campylobacter jejuni strains of importance for the epidemiology of C jejuni in Danish broiler chickens. Four C. jejuni strains were selected for experimental colonization studies in day-old and 14-day-old chickens hatched from specific pathogen free (SPF) eggs. Of the four C. jejuni strains tested, three were Penner heat-stable serotype 2, flaA type 1/1, the most common type found among broilers and human cases in Denmark. The fourth strain was Penner heat-stable serotype 19, which has been shown to be associated with the Guillain Barré Syndrome (GBS) in humans. The minimum dose for establishing colonization in the day-old chickens was approximately 2 cfu, whereas two- to threefold higher doses were required for establishing colonization in the 14-day-old chickens. Two of the C. jejuni strains were shown to be invasive in orally challenged chickens as well as in three different human epithelial cell lines.
Imprenta: Avian Diseases, v. 50, n. 1, p. 10-14, 2006
Identificador do objeto digital: 10.1637/7376-051005R.1
Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Transmission ; Guillain-Barre Syndrome - Epidemiology
Data de publicação: 2006